The 2021 NFL regular season schedule was released last night, and the Tennessee Titans have the 13th-hardest schedule in the league. The Titans will have nine matchups against 2020 playoff teams. A midseason five-game stretch will be filled with tough games, as they will host the Buffalo Bills on October 18th, followed by a home matchup with the Kansas City Chiefs, road games against the Indianapolis Colts and Los Angeles Rams, and another home game against the New Orleans Saints on November 14th. Tennessee opens the season against the Arizona Cardinals at home on September 12th.